Experimental analysis of Helicobacter pylori transcriptional terminators suggests this microbe uses both intrinsic and factor-dependent termination
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چکیده
منابع مشابه
Rho-dependent terminators and transcription termination.
Rho-dependent transcription terminators participate in sophisticated genetic regulatory mechanisms, in both bacteria and phages; they occur in regulatory regions preceding the coding sequences of genes and within coding sequences, as well as at the end of transcriptional units, to prevent readthrough transcription. Most Rho-dependent terminators have been found in enteric bacteria, but they als...
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Mobile DNAs use many mechanisms to minimize damage to their hosts. Here we show that a subclass of group II introns avoids host damage by inserting directly after transcriptional terminator motifs in bacterial genomes (stem-loops followed by Ts). This property contrasts with the site-specific behavior of most group II introns, which insert into homing site sequences. Reconstituted ribonucleo pr...
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Nowadays medicines believe that the only definite method to diagnose the existence of Helicobacter pylori microbe is performing endoscope, however it’s painful and insufferable for young children. Thus in this paper we used data mining algorithms to diagnose the existence of this microbe and eventually we succeeded in predicting the existence of this bacterium in stomach that guides medicines t...
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Helicobacter pylori is a gram negative bacterium that has been linked to numerous severe gastroduodenal diseases, including peptic ulcer and gastric cancer. The basis for these diverse clinical outcomes is not understood, but part of the explanation may be differential virulence among strains. A considerable number of strain specific genes have been revealed by comparative genomics studies of t...
متن کاملRegulation of the elongation-termination decision at intrinsic terminators by antitermination protein N of phage lambda.
The mechanisms that control N-protein-dependent antitermination in the phage lambda life cycle have counterparts in the regulatory systems of other organisms. Here we examine N-dependent antitermination at the intrinsic tR' terminator of lambda to elucidate the regulatory principles involved. The tR' terminator consists of a sequence of six base-pairs along the template at which the transcripti...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2007
ISSN: 0950-382X
DOI: 10.1111/j.1365-2958.2007.06033.x